The primary disadvantage of analog signaling is that any system has noise – i.e., random unwanted variation. As the signal is copied and re-copied, or transmitted over long distances, these apparently random variations become dominant. Electrically, these losses can be diminished by shielding, good connections, and several cable types such as coaxial or twisted pair.

The effects of noise create signal loss and distortion. This is impossible to recover, since amplifying the signal to recover attenuated parts of the signal amplifies the noise (distortion/interference) as well. Even if the resolution of an analog signal is higher than a comparable digital signal, the difference can be overshadowed by the noise in the signal.

Most of the analog systems also suffer from generation loss.