Enabling access to Web content for all users is the concern of the Web accessibility movement. Websites can be designed to be more accessible by their conformance to certain design principles.

Screen readers are of limited use when reading text from websites designed without consideration to accessibility; this can be due to the differences between spoken and written language and the complexity of text, but it is mainly due to poor page design practices. The tendency to indicate semantic meaning using methods that are purely presentational (e.g. larger or smaller font sizes, using different font colors, or images or multimedia to provide information) restricts meaningful access to some users. Therefore designing sites in accordance with Web accessibility principles helps enable meaningful access for all users.

For example, web designers can ensure that navigation and content is as plain and simple as appropriate and long texts should provide summaries.